Genetic and Structural Disease Screening Tests

Overview

At Animal Republic Veterinary Hospital and ER, we understand the importance of early detection and prevention when it comes to the health of your pet. Certain dog and cat breeds are predisposed to specific genetic conditions or structural issues that can significantly impact their quality of life. To help ensure your pet lives a long, healthy life, we recommend genetic tests and imaging studies for these breeds while they are young.

Genetic Tests for Dogs and Cats

Degenerative Myelopathy (DM)

• Breeds: German Shepherds, Boxers, Pembroke Welsh Corgis
• Overview: DM is a progressive neurological disorder that typically begins in the hind limbs, leading to muscle wasting and loss of coordination. Affected dogs usually present clinical signs in adulthood and eventually lose the ability to walk.

Progressive Retinal Atrophy (PRA)

• Breeds: Labrador Retrievers, Poodles, Cocker Spaniels
• Overview: PRA is a genetic condition that leads to blindness. Dogs typically show signs of visual impairment between 5 and 12 years of age, with an average onset around 10 years.

Exercise-Induced Collapse (EIC)

• Breed: Labrador Retrievers
• Overview: EIC is a condition where affected dogs may collapse after intense exercise. Signs usually appear after 5-20 minutes of strenuous activity.

Polycystic Kidney Disease (PKD)

• Breeds: Persian, Persian Crosses, British Longhair and Shorthair, Exotic Longhair and Shorthair, Himalayan, Maine Coon, Napoleon, Ragdoll, Scottish Fold, Scottish Straight, Devon Rex
• Overview: PKD is a genetic condition that can lead to kidney failure. Early detection through genetic testing is crucial for managing this condition effectively.

Hypertrophic Cardiomyopathy (HCM)

• Breed: Ragdolls
• Overview: HCM is characterized by the thickening of the heart muscle. Genetic testing helps identify the risk and guide preventive care.

Glycogen Storage Disease (GSD IV)

• Overview: GSD IV is a rare metabolic disorder affecting the storage and use of glycogen in the body. Affected kittens may die soon after birth, while others may develop muscle tremors, muscle atrophy, and later death.

X-Rays for Structural Screening

Hip Dysplasia Screening

• Breeds: German Shepherds, Golden Retrievers, Labrador Retrievers, Maine Coons, Persian Cats
• Overview: Hip dysplasia can lead to arthritis and mobility issues. Early X-rays can detect signs of this condition, which is less common in cats but still significant for affected breeds.

Elbow Dysplasia Screening

• Breeds: Bernese Mountain Dogs, Rottweilers, Labrador Retrievers
• Overview: Elbow dysplasia is a joint disorder that can lead to pain and lameness. Early detection through X-rays can help manage or prevent progression.

Patellar Luxation Screening

• Breeds: Yorkshire Terriers, Pomeranians, Boston Terriers, Abyssinians Cats, Devon Rex Cats
• Overview: Patellar luxation occurs when the kneecap dislocates. X-rays can help identify early signs, which can lead to mobility issues if untreated.

Spinal X-rays

• Breed: Scottish Folds
• Overview: Scottish Folds are prone to osteochondrodysplasia, affecting bone and cartilage development. Spinal X-rays help detect and manage this condition early.

Why Early Screening Matters

Early genetic testing and imaging studies are crucial for detecting and managing these conditions before they progress. By identifying potential health risks early, you can take proactive steps to ensure your pet receives the necessary care and treatment, improving their quality of life.